Researchers Uncover New Insights Into Collateral Blood Flow in CTEPH Patients

As the supplier of the body’s blood, the heart must also supply its own blood to keep itself nourished and oxygenated. The heart’s blood supply comes from the coronary arteries, which receive oxygenated blood from the pulmonary veins. Normally, the heart receives enough oxygenated blood, but with chronic thromboembolic pulmonary hypertension (CTEPH) is present, a clot may obstruct blood flow.

 

Fortunately, the body has a “plan B” for ensuring the heart receives an adequate blood supply, and this mechanism is known as collateral blood flow. Collateral blood flow describes a redundant flow of blood in which branches between adjacent blood vessels bypass a blockage in another vessel in order to supply enough oxygenated blood to tissue, such as the heart, downstream of the blockage. When collateral blood flow acts to supply blood to the heart, the vessels are known as coronary artery-pulmonary artery collaterals.

The prevalence and predictors of coronary artery-pulmonary artery collaterals in CTEPH are not well understood. Due to the fact that such an important, life-saving mechanism is important to understand, a team of researchers from the University of California, San Diego investigated coronary artery-pulmonary artery collaterals in CTEPH patients. Their research was published in an article titled, “Prevalence of Coronary Artery-Pulmonary Artery Collaterals in Patients with Chronic Thromboembolic Pulmonary Hypertension,” in the journal Pulmonary Circulation.

The team studied 259 patients with CTEPH to identify coronary artery-pulmonary artery collaterals. In order to detect the presence of these vessels, the researchers evaluated //www.heart.org/idc/groups/heart-public/@wcm/@hcm/documents/downloadable/ucm_300436.pdf" rel="nofollow" target="_blank" style="border: 0px; font-family: inherit; font-style: inherit; font-weight: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: rgb(187, 85, 81); text-decoration: none; transition: all 0.2s ease;">coronary angiograms, in which CTEPH patients had a special X-ray contrast dye injected through a catheter into the arteries in order for their arteries to show up on X-rays. Looking at these X-rays, the researchers noted that 10.8% of CTEPH patients had coronary artery-pulmonary artery collaterals, whereas only one control subject (0.4%) had collaterals. When comparing CTEPH patients with and without collaterals, the CTEPH patients more frequently had total occlusion of either the right or left main pulmonary artery or lobar arteries, indicating that the collaterals formed to rescue blood flow to the heart.

The researchers believe that identifying the presence of collaterals in CTEPH patients hold diagnostic and prognostic value. Since collaterals indicated greater pulmonary artery obstructions, a coronary angiogram may be used to help detect CTEPH in suspect patients.

Comment

  • Alfredmoimi Alfredmoimi Thursday, 18 June 2015

    wh0cd959710 sildenafil price Furosemide

  • Julie Julie Thursday, 18 June 2015

    Generika bestellen ohne kreditkarte und generika rezeptfrei online bestellen, kaufen ohne rezept deutschland und auch gunstig
    kaufen per nachnahme, billig kaufen deutschland. Ohne rezept rezeptfrei und rezeptfrei gunstig, kaufen holland und auch spritze preis, deutschland.

  • AaronJuilt AaronJuilt Thursday, 18 June 2015

    wh0cd22110 augmentin 875 mg cheapest abilify sildenafil citrate 100mg pills

  • CharlesCig CharlesCig Thursday, 18 June 2015

    wh0cd765950 Azithromycin Prescriptions

  • Kennethcen Kennethcen Thursday, 18 June 2015

    wh0cd378430 viagra mastercard

  • Dominic Dominic Thursday, 18 June 2015

    Generika rezeptfrei kaufen deutschland und generika kaufen preisvergleich, online bestellen mit rezept und
    auch pflaster preisvergleich, generika bestellen schweiz.
    Apotheke preisvergleich und fu?pilz once preis, ampullen preis und auch kosten rezept, generika paypal.

  • Reina Reina Thursday, 18 June 2015

    Generika preisvergleich rezeptfrei und kann man ohne rezept apotheke kaufen,
    generika online deutschland und auch kaufen deutschland paypal, ohne rezept legal
    kaufen. Online kaufen serios und generika esomeprazol, online apotheke und auch pil bestellen, wo bestellen.

  • Hugo Hugo Thursday, 18 June 2015

    Original rezeptfrei in deutschland kaufen und auf rechnung kaufen ohne rezept, zulassung deutschland erwachsene und auch gunstig
    per uberweisung, kaufen in deutschland. Dose preisvergleich und bestellen deutschland, witze kostenlos und auch billig kaufen,
    bester preis.

  • CharlesCig CharlesCig Thursday, 18 June 2015

    wh0cd184670 vardenafil online

  • CharlesCig CharlesCig Thursday, 18 June 2015

    wh0cd184670 buy nolvadex vardenafil

Leave your comment

Make sure you enter the (*) required information where indicated. HTML code is not allowed.

About Us

The Saudi Association for Pulmonary Hypertension (SAPH) is a medical and research national group of many medical specialists, who shared a common interest in the field of pulmonary vascular disease. The main goal for SAPH is to increase the awareness and the knowledge of pulmonary vascular diseases in the society and between the medical professionals.

The Saudi Association for Pulmonary Hypertension (SAPH) is a Subsidiary of The

Saudi Association for PH

STS office (Exit 11 & the Airport Road)

Riyadh, Saudi Arabia

P. O. Box 106911
Riyadh 11676
Saudi Arabia

Tel:+966-11-2488966
Fax: +966-11-2487431
Mobile:+966506426704

We use cookies to improve our website. By continuing to use this website, you are giving consent to cookies being used. More details…