Researchers Uncover New Insights Into Collateral Blood Flow in CTEPH Patients

As the supplier of the body’s blood, the heart must also supply its own blood to keep itself nourished and oxygenated. The heart’s blood supply comes from the coronary arteries, which receive oxygenated blood from the pulmonary veins. Normally, the heart receives enough oxygenated blood, but with chronic thromboembolic pulmonary hypertension (CTEPH) is present, a clot may obstruct blood flow.

 

Fortunately, the body has a “plan B” for ensuring the heart receives an adequate blood supply, and this mechanism is known as collateral blood flow. Collateral blood flow describes a redundant flow of blood in which branches between adjacent blood vessels bypass a blockage in another vessel in order to supply enough oxygenated blood to tissue, such as the heart, downstream of the blockage. When collateral blood flow acts to supply blood to the heart, the vessels are known as coronary artery-pulmonary artery collaterals.

The prevalence and predictors of coronary artery-pulmonary artery collaterals in CTEPH are not well understood. Due to the fact that such an important, life-saving mechanism is important to understand, a team of researchers from the University of California, San Diego investigated coronary artery-pulmonary artery collaterals in CTEPH patients. Their research was published in an article titled, “Prevalence of Coronary Artery-Pulmonary Artery Collaterals in Patients with Chronic Thromboembolic Pulmonary Hypertension,” in the journal Pulmonary Circulation.

The team studied 259 patients with CTEPH to identify coronary artery-pulmonary artery collaterals. In order to detect the presence of these vessels, the researchers evaluated //www.heart.org/idc/groups/heart-public/@wcm/@hcm/documents/downloadable/ucm_300436.pdf" rel="nofollow" target="_blank" style="border: 0px; font-family: inherit; font-style: inherit; font-weight: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: rgb(187, 85, 81); text-decoration: none; transition: all 0.2s ease;">coronary angiograms, in which CTEPH patients had a special X-ray contrast dye injected through a catheter into the arteries in order for their arteries to show up on X-rays. Looking at these X-rays, the researchers noted that 10.8% of CTEPH patients had coronary artery-pulmonary artery collaterals, whereas only one control subject (0.4%) had collaterals. When comparing CTEPH patients with and without collaterals, the CTEPH patients more frequently had total occlusion of either the right or left main pulmonary artery or lobar arteries, indicating that the collaterals formed to rescue blood flow to the heart.

The researchers believe that identifying the presence of collaterals in CTEPH patients hold diagnostic and prognostic value. Since collaterals indicated greater pulmonary artery obstructions, a coronary angiogram may be used to help detect CTEPH in suspect patients.

Comment

  • EugeneDyemy EugeneDyemy Thursday, 18 June 2015

    wh0cd109150 cephalexin 250 mg arimidex amoxil without prescription

  • MichaeltOums MichaeltOums Thursday, 18 June 2015

    wh0cd334110 albuterol crestor 10mg price nexium generic for abilify propranolol online pharmacy furosemide celexa

  • CharlesCig CharlesCig Thursday, 18 June 2015

    wh0cd140350 generic atenolol Levothyroxine 50 Mcg

  • Alvin Alvin Thursday, 18 June 2015

    You could definitely see your enthusiasm in the work you write.
    The world hopes for more passionate writers such as you who are not afraid to mention how they believe.
    At all times follow your heart.

  • Russell Russell Thursday, 18 June 2015

    Ahaa, its nice conversation concerning this article at
    this place at this website, I have read all that, so at this time me also commenting here.

  • CharlesCig CharlesCig Thursday, 18 June 2015

    wh0cd884190 triamterene 25 mg

  • Alfredmoimi Alfredmoimi Thursday, 18 June 2015

    aceon

  • WilliamGoart WilliamGoart Thursday, 18 June 2015

    Howdy! generic viagra great web site.

  • Tracynem Tracynem Thursday, 18 June 2015

    wh0cd496670 buy levaquin FLAGYL ONLINE anafranil Ciprofloxacin HCL allopurinol

  • BennySpich BennySpich Thursday, 18 June 2015

    buy aceon

Leave your comment

Make sure you enter the (*) required information where indicated. HTML code is not allowed.

About Us

The Saudi Association for Pulmonary Hypertension (SAPH) is a medical and research national group of many medical specialists, who shared a common interest in the field of pulmonary vascular disease. The main goal for SAPH is to increase the awareness and the knowledge of pulmonary vascular diseases in the society and between the medical professionals.

The Saudi Association for Pulmonary Hypertension (SAPH) is a Subsidiary of The

Saudi Association for PH

STS office (Exit 11 & the Airport Road)

Riyadh, Saudi Arabia

P. O. Box 106911
Riyadh 11676
Saudi Arabia

Tel:+966-11-2488966
Fax: +966-11-2487431
Mobile:+966506426704

We use cookies to improve our website. By continuing to use this website, you are giving consent to cookies being used. More details…