An Exciting Time for Research into CTEPH Discussed in Review Article

Patients with pulmonary hypertension may be surprised to know that the disease can sometimes be accompanied by the complication known as thromboembolic pulmonary hypertension (CTEPH). Pulmonary embolisms are the root cause of CTEPH because a pulmonary embolism (a blood clot in the lungs) that fails to be degraded via thromboembolysis can become lodged in blood vessels leading to the lungs and occlude blood flow. Individuals without any history of pulmonary embolisms are susceptible to CTEPH, making it important to understand the pathophysiology, risks factors, and signs of CTEPH.

 

As suggested by a recent review entitled, “Chronic Thromboembolic Pulmonary Hypertension: the End Result of Pulmonary Embolism,” which was published in Current Cardiology Reports, it is an exciting time for researchers in the field of CTEPH and patients who suffer from the disease. A lot of progress has been made in understanding CTEPH, leading to better diagnosis techniques and therapeutic options.

“Although it is generally believed that CTEPH originates with acute venous thromboembolism, interestingly, up to 40% of CTEPH patients will have no antecedent history suggestive of acute pulmonary embolism,” wrote Dr. Alison S. Witkin and Dr. Richard N. Channick, of the Division of Pulmonary and Critical Care Medicine at Massachusetts General Hospital in Boston.

Often times, CTEPH symptoms are confused with those of other cardiac and pulmonary diseases, which can lead to delays between first notice of symptoms and CTEPH diagnosis. Shortness of breath, progressive exercise intolerance, and chest pain are all indicators of some form of pulmonary hypertension. However, a large difference between pulmonary arterial hypertension and CTEPH is the type of blood vessels that are affected. Pulmonary arterial hypertension affects blood vessels smaller than 300 micrometers in size, while CTEPH affects larger blood vessels that are closer to the heart.

Since patients and their clinicians may not suspect CTEPH is the root cause of symptoms due to the disconnect between patient history and the ease of coming to an improper diagnose, it is important to have a standard technique to diagnose CTEPH. Commonly, ventilation perfusion scans are used to suggest CTEPH, but the gold standard to properly diagnose CTEPH is via right heart catheterization and pulmonary artery angiogram. These may be performed when patients have the indicative symptoms for CTEPH and have some of the common risk factors: idiopathic pulmonary embolism, large perfusion defects, and a right ventricular systolic pressure greater than 50 mmHg.

Once properly diagnosed, CTEPH, unlike other forms of pulmonary hypertension, can be cured by the surgical procedure known as pulmonary thromboendarterectomy (PTE). Recently, a medication developed by Bayer, Adempas (riociguat), was approved by the Food and Drug Administration for patients with CTEPH. Adempas is also indicated for pulmonary arterial hypertension, as the drug acts to increase vessel diameter to allow blood to flow more easily, reducing the pressure the heart must work against to pump blood to the lungs.

Because there are viable treatment options for those with CTEPH, the most significant unmet medical need for addressing the disease is improving early detection, since patient outcomes are hinged on how early an accurate CTEPH diagnosis is made. With researchers making substantial progress in improving early detection of CTEPH, the medical community is becoming increasingly capable of treating and curing people with the disease.

Comment

  • Michaelplups Michaelplups Thursday, 02 July 2015

    If you want a person's mission to become prepared swift in addition to without having blunders the destination for yourself. Our reasonably priced tailor made essay creating company can be very helpful for every pupil who's got no time or want to deal with essays. We know that learners right this moment be required to offer with rather more courses, books, papers and professors. That's why we would like to help make it somewhat more convenient for you with our essay creating enable. Not everyone seems to be prepared to sit for several hours and power their creativeness and creativity to attempt the things they refuse to undertake.
    http://saptodjojokartiko.com/get-better-at-blogger-essay-custom-producing/

  • Michaelplups Michaelplups Thursday, 02 July 2015

    If you need ones own assignment being composed quickly in addition to without any problems the position for you. Our low-budget custom essay composing company could in fact be beneficial for every university student who may have no time or wish to cope with essays. We recognize that college students nowadays really have to deal with much more lessons, publications, papers and professors. That's why we want to produce it somewhat a lot easier to suit your needs with our essay producing facilitate. Not everyone seems to be ready to sit for hours and drive their creativeness and creativity to perform whatever they refuse to carry out.
    http://www.impulseholidays.in/?p=2109

  • viagra without doctor visit viagra without doctor visit Thursday, 02 July 2015

    http://viagra-withoutadoctor.org/ viagra without a doctor prescription begins functioning in by the skin of one's teeth a only one 30 minutes and also supports as far as something too extended since divers hours and in totting up extend the specially sensual pursuit simply close 2-3 instances. The essential wee atom of ingredient start in Prejac permits past help better the dissemination of blood to the men the reproductive system that assists to clear more than impotence.

  • Abaalgonee Abaalgonee Thursday, 02 July 2015

    cialis time to work hy vee pharmacy sioux falls how female viagra works cost of cialis vs viagra kroger pharmacy number buy generic viagra online overnight erectile dysfunction in men over 40 urology erectile dysfunction

  • cialis costs cialis costs Thursday, 02 July 2015

    There are numerous reasons why women masquerade this http://cialiswalmart.top/ levitra over the counter at walmart condition. There are a crowd of reasons that stir a womans libido. Increasing stress at put through, retirement community, economical, social, mental pressures are some of the reasons that ignite the form at perfectly an early grow older in women.

  • tadalafil over the counter at walmart tadalafil over the counter at walmart Thursday, 02 July 2015

    There are numerous reasons why women masquerade this http://cialiswalmart.top/ cialis pricing walmart condition. There are a crowd of reasons that affect a womans libido. Increasing stress at effort, skilled in, conservative, communal, intellectual pressures are some of the reasons that ignite the form at perfectly an ahead of time age in women.

  • Liontup Liontup Thursday, 02 July 2015

    Отопление в ликино дулёво http://moskva-elisa.ru/kubinka.html сколько стоит провести канализацию в частном доме http://montazh-elisa.ru/goroda/naro-fominsk.html монтаж систем отопления луховицы http://otoplenie-elisa.ru/montazh-radiatorov.html установка канализации талдом http://ustanovka-elisa.ru/kolomna.html установка канализации волоколамск http://santeh-elisa.ru/stupino.html

  • erectile-tissue-in-the-male erectile-tissue-in-the-male Thursday, 02 July 2015

    http://safe-store-us.com/#sildenafil-vs-tadalafil-vs-vardenafil - mn board of pharmacy accelerated pharmacy programs http://usa-best-store.com/#usc-pharmacy - viagra tablet smoking causes erectile dysfunction http://safe-shopping-us.com/#walmart-pharmacy-winder-ga - sam club pharmacy caffeine and erectile dysfunction http://safe-store-us.com/#erectile-dysfunction-at-22 - where can i purchase viagra tadalafil doses

  • tadalafil no prescription tadalafil no prescription Thursday, 02 July 2015

    Existence of the ED sufferer becomes drastically faked as it keeps him from indulging in interaction satisfactorily and incurs unconscious disturbances such as emphasis on, pit and low lustful confidence. http://cialis-withoutadoctorsprescription.top/ cialis without a prescription is a physic, which works at the root prime mover and provides infertile men with the of the essence penile resolution in search having gender pleasurably while also ensuring that the companion is satisfied.

  • Michaelplups Michaelplups Thursday, 02 July 2015

    This is the assistance all learners will want many times - a real top notch to jot down their essays for them. The tailor made essay crafting support may help you begin distributing your writing duties by the due date also to meet all of the conditions within your professors. And it's so convenient - purchasing a tailor made essay normally requires only some minutes and may prevent so much time, stress and anxiety and challenges. There'll be someone else to deal with your activity therefore you can rest for quite a while.
    http://www.hajjramssportsconsult.com/royal-essays-penning-support-skilled-effectively/

Leave your comment

Make sure you enter the (*) required information where indicated. HTML code is not allowed.

About Us

The Saudi Association for Pulmonary Hypertension (SAPH) is a medical and research national group of many medical specialists, who shared a common interest in the field of pulmonary vascular disease. The main goal for SAPH is to increase the awareness and the knowledge of pulmonary vascular diseases in the society and between the medical professionals.

The Saudi Association for Pulmonary Hypertension (SAPH) is a Subsidiary of The

Saudi Association for PH

STS office (Exit 11 & the Airport Road)

Riyadh, Saudi Arabia

P. O. Box 106911
Riyadh 11676
Saudi Arabia

Tel:+966-11-2488966
Fax: +966-11-2487431
Mobile:+966506426704

We use cookies to improve our website. By continuing to use this website, you are giving consent to cookies being used. More details…